Berberine is an alkaloid that is present in a number of plants, including Berberis vulgaris (barberry), Berberis aristata (tree turmeric), Berberis aquifolium (Oregon grape), Hydrastis canadensis (goldenseal), and Coptis chinensis (goldthread). This important plant extract demonstrates important benefits for glucose metabolism, maintenance of healthy lipid levels, insulin sensitivity, cardiac support, weight management, gastrointestinal health, immune modulation, and cognitive support.