Reduced glutathione, most commonly called glutathione or GSH, is a relatively small molecule ubiquitous in living systems. Occurring naturally in all human cells, GSH is a water-phase orthomolecule. Its intracellular depletion ultimately results in cell death, and its clinical relevance has been researched for decades. Recent research suggests that reduced glutathione may be an even more effective antioxidant than vitamins C and E, and it is considered the “master antioxidant.”

GSH protects tissues by neutralizing free radicals and improves the immune system by promoting antigen presentation and stimulating CD8 cells. Glutathione is involved in various important liver detoxification processes, amino-acid transport, production of coenzymes, and the recycling of vitamins C and E.